British Air Force Typhoon FGR4s have operated alongside French warplanes in a joint strike targeting an subterranean weapons facility in Syrian territory employed by the Daesh militant organization, according to the UK Ministry of Defence.
The location, pinpointed through intelligence, was thought to be housing weapons and explosive materials, the release indicated, and was positioned in mountainous terrain just north of Palmyra in central Syria.
"Our fighter planes employed precision-guided Paveway IV munitions to target a series of approach shafts providing entry to the facility... initial indications indicate the target was engaged successfully," the ministry announced.
There was no evidence of any harm to civilians in the strike late on Saturday and every plane involved made a safe return, the defence officials confirmed.
The Typhoon FGR4s were supported by a Voyager refuelling tanker.
The Islamic State group - also known as Daesh - enforced jihadist rule over significant areas in both Syria and Iraq prior to its 2019 collapse.
"This action underscores our UK leadership, and determination to operate in unison with our partners, to eliminate any re-emergence of IS and their harmful and extremist ideologies in the Middle East," UK Defence Secretary John Healey said.
British military aircraft have performed surveillance missions over Syrian airspace to "forestall any attempted resurgence" of IS after its military defeat at the climactic battle in Baghuz in 2019, the ministry said.
"I want to thank all the members of British forces involved in this mission for their professionalism and their courage," he added. "Including them were a great many British troops stationed over the festive period. This mission, to eliminate dangerous terrorists who threaten our way of life, shows how British military are always on standby, continuously, ensuring Britain's security within its borders and strong abroad."
In December, the American forces carried out what it termed a "major assault" on IS targets in Syria, subsequent to an assault resulted in the deaths of two US troops and a civilian interpreter in Palmyra.
The United Nations estimates IS still has between 5,000 and 7,000 militants in Iraq and Syria.